Oral anticoagulants are the treatment of choice for the prevention of stroke related to atrial fibrillation. Novel anticoagulants are now available and should be considered in suitable patients.
- Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia.
- Strokes associated with AF often cause substantial neurological disability and mortality.
- Antithrombotic therapy is the mainstay for stroke prevention.
- Until recently, warfarin was the only effective oral anticoagulant available.
- Novel anticoagulants are safe and easy to use.