Feature Article

Evolving therapies for atrial fibrillation: focus on embolic stroke

Rajeev Pathak, Rajiv Mahajan, Prashanthan Sanders



Oral anticoagulants are the treatment of choice for the prevention of stroke related to atrial fibrillation. Novel anticoagulants are now available and should be considered in suitable patients.

Key Points

  • Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia.
  • Strokes associated with AF often cause substantial neurological disability and mortality.
  • Antithrombotic therapy is the mainstay for stroke prevention.
  • Until recently, warfarin was the only effective oral anticoagulant available.
  • Novel anticoagulants are safe and easy to use.