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Perspectives

Atrial fibrillation and concomitant CAD: an individualised approach to combined antithrombotic therapy

LOUISE SEGAN, John Amerena

Figures

© PHANIE/VOISIN/DIOMEDIA.CO
© PHANIE/VOISIN/DIOMEDIA.CO

Abstract

An individualised approach to antithrombotic management should be adopted in patients with atrial fibrillation and concomitant coronary artery disease with consideration to both bleeding and thrombotic risk.

Key Points

  • One in five patients receiving long-term anticoagulation have coronary artery disease.
  • These patients present a unique challenge in balancing the risks and benefits of combined anticoagulant and antiplatelet therapies.
  • The efficacy and safety of combination antiplatelet and anticoagulant therapies have been assessed recently in several trials.
  • An individualised approach to antithrombotic management should be adopted in patients with dual indications, typically those with pre-existing nonvalvular atrial fibrillation presenting with an acute coronary syndrome, with consideration to both bleeding and thrombotic risks.

Figures

© PHANIE/VOISIN/DIOMEDIA.CO
© PHANIE/VOISIN/DIOMEDIA.CO